Chromatography Online
Practical advice, tutorials, and peer-reviewed research on liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS) and related techniques.
About LCGC International - Chromatography Online
Jan 1, 2019 · Founded in 1983, LCGC International is the leading provider of digital and print content to the separation science market, enhancing the productivity, efficiency, and the overall value of separation techniques globally.
Certificate of Analysis (CoA) and Calculations for Small-Molecule …
Jun 10, 2024 · This article describes the contents and associated calculations of CoAs for small-molecule drugs. It explains how these documents help to ensure drug quality in the supply chain.
LCGC International - Chromatography Online
Practical advice, tutorials, and peer-reviewed research on liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS) and related techniques.
Ultraviolet Detectors: Perspectives, Principles, and Practices
Oct 1, 2019 · The authors provide a technical overview of the design and operating principles of variable wavelength and photodiode array detectors, and include historical perspectives and common practices in operation and maintenance.
LCGC Europe - Chromatography Online
Practical advice, tutorials, and peer-reviewed research on liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS) and related techniques.
Modern Trends and Best Practices in Mobile-Phase Selection in …
Oct 1, 2018 · Modern trends in LC mobile-phase selection and preparation include using simpler mobile phases, increased use of MS-compatible mobile phases, and eliminating filtration and certain mobile-phase additives. Here, we discuss those and other trends and best practices, as well as the fundamentals behind them.
Troubleshooting Basics, Part IV: Peak Shape Problems
Jul 1, 2012 · In a well-behaved method, changes in peak shape should occur gradually over hundreds or thousands of samples. Tailing of one or a few peaks usually points to a problem.
LCGC North America - Chromatography Online
Practical advice, tutorials, and peer-reviewed research on liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS) and related techniques.
The Limit of Detection - Chromatography Online
Feb 1, 2009 · The concept of the limit of detection (LOD) has been, and still is, one of the most controversial in analytical chemistry. The multiple definitions and calculation methods proposed have contributed to this situation. Although in the last years, several international organizations, such as ISO or IUPAC, have tried to reach a consensus in their definitions and have issued …