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Uncovering Key Differences Between Humans and Mice in Cancer Immunotherapy Targets
Programmed cell death protein 1,” or PD-1, has been considered a key target in cancer therapies since its discovery in the ...
Scientists unveil surprising human vs. mouse differences in a major cancer immunotherapy target
Since its discovery in the 1990s, programmed cell death protein 1 (PD-1) has been regarded as a leading target in cancer ...
C&EN3d
Flawed assumptions could be spoiling cancer immunotherapy research
Cancer immunotherapy drugs called immune checkpoint inhibitors take the brakes off the body’s immune system, allowing it to ...
Armed robbery in Revesby1h
Self-Destruction Of Glioblastoma
Januar 2025A team of Jülich scientists used a special RNA molecule to specifically attack and destroy glioblastoma cancer cells. The selectively ...
Breakthrough Discovery Reveals Hidden Flaws in Cancer Research Models
Scientists have discovered significant discrepancies in PD-1 between humans and rodents, indicating that common lab models ...
SMA22h
Raising SMN protein levels may be helpful early step in SMA treatment
Combining a premade SMN protein with a Spinraza-like drug (targets SMN2 gene) helped patient-derived motor neurons; potential ...
Pharmaceutical Technology9d
GXP-1 by Egret Therapeutics for Transplant Rejection: Likelihood of Approval
GXP-1 is under clinical development by Egret Therapeutics and currently in Phase I for Transplant Rejection. According to GlobalData, Phase I drugs for Transplant Rejection have an 84% phase ...
Phys.org19d
Introducing perceptein, a protein-based artificial neural network in living cells
Westlake University in China and the California Institute of Technology have designed a protein-based system ... to stay alive or undergo programmed cell death. Cells naturally process multiple ...
C&EN22d
A protein-based neural network for cells
In this case, the protein-based neural network allows the comparison of multiple inputs and provides a single output, such as programmed cell death or differentiation. A neural network ...
Medindia2d
Artificial Intelligence Transforming Glaucoma Drug Discovery
Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model ...
Business Wire13d
TEVIMBRA Approved in U.S. for First-line Treatment of Gastric and Gastroesophageal Junction Cancers in Combination with Chemotherapy
BeiGene, Ltd. (NASDAQ: BGNE; HKEX: 06160; SSE: 688235), a global oncology company that intends to change its name to BeOne Medicines Ltd., today annou ...