RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut ...

This study is the first to demonstrate that certain tRNA introns influence gene expression. Scientists have discovered that ...

Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts.

RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which ... ribosomal and small nuclear RNA (tRNA, rRNA, snRNAs) fold into unique structures ...

The crystal structure of pseudouridine synthase I from Escherichia coli, which, for example, modifies positions 38, 39 and/or 40 in tRNA, reveals a dimeric protein that contains two positively ...

These work by binding to specific mRNA sequences in order to modify gene expression. By correcting faulty RNA processing through altering splicing – a process that involves the joining together and ...

The candidate uses the same basic mRNA technology implemented in Moderna’s covid-19 vaccines to accomplish this. mRNA vaccines prompt the body’s cells to produce a target protein that’s then ...

Using Quick-irCLIP and alternative polyadenylation (APA) Seq, we show eIF3 crosslinks predominantly with 3’ untranslated region (3’-UTR) termini of multiple mRNA isoforms ... were used as the rRNA ...

Protein synthesis is a central process in microorganisms and is heavily targeted by antimicrobials. Studies of transfer RNAs (tRNAs), aminoacyl-tRNA synthetases (aaRSs), and ribosomes have led to ...