Northwestern Medicine scientists have uncovered new details explaining how poxviruses manipulate host cells to enhance their ...
In this valuable study, Roiuk et al employed a combination of ribosome profiling and reporter assays to provide convincing evidence that eIF2A is not involved in translational regulation in cultured ...
In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.
A team of scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the University of ...
Benitec has a market cap of $250mn, $67.8mn in cash, and a cash runway of over 10 quarters, but faces risks due to its small ...
Ramakrishnan, a distinguished structural biologist and Nobel Laureate in Chemistry (2009), is renowned for his groundbreaking ...
Flagship Pioneering partners with CUHP and MTI to advance research, clinical translation, and talent development in the UK. The collaboration gives Flagship’s companies access to Cambridge’s resources ...
Scientists have unveiled insights into how HIV-1, the virus responsible for AIDS, skillfully hijacks cellular machinery for its own survival. By dissecting the molecular interplay between the virus ...
Harness Therapeutics Ltd. has raised fresh financing to further develop its technology for upregulating the translation of ...
Researchers mapped HIV-1’s translation strategy, revealing RNA elements like uORFs, iORFs and an intricate frameshift site ...
pre-mRNA processing, translation and mRNA degradation. Replication-dependent histone genes contain no introns, and the only pre-mRNA processing step is an endonucleoytic cleavage to form the 3 ...
Regulation of the poly(A) tail is essential for selective protein translation in early embryos. However, the mechanisms that determine and maintain the length of maternal mRNA poly(A) tails remain ...