In trials at University College London Hospitals (UCLH), an ASO is being used to target the mutated gene that results in the ...

The Kowalinski group at EMBL Grenoble discovered notable differences between the nuclear cap-binding complex in trypanosomes and humans, a critical component in cellular RNA metabolism. Trypanosomes ...

Cohn said mRNA degrades extremely quickly in the body and has no effect on a cell’s nucleus or DNA. It affects muscle cells, ...

Delve into the increasingly dynamic landscape of ALS treatment development with thirteen companies advancing candidates in ...

Trypanosomes are parasites that cause sleeping sickness, Chagas disease, and various animal diseases. Diagnosis and treatment remain complex and no effective vaccine has been developed. A better ...

Scientists at the University of California, Irvine, have discovered that nuclear speckles, a membraneless organelle within the nucleus, serve as central hubs for pre-mRNA 3′ end processing.

The plasmid vector is taken up into cells and transcribed in the nucleus (1). The single stranded mRNA (2) is translated into protein in the cytoplasm. The DNA vaccine-derived protein antigen (3 ...

The bill's sponsor said that restriction was “an error,” and that she intends to change it if it were to move forward in the ...

Mysterious Blobs Found inside Cells Are Rewriting the Story of How Life Works Tiny specks called biomolecular condensates are ...

Drugs targeting amyloid plaques have failed to show efficacy in clinical trials. A new approach is needed to tackle AD ...