Now, it’s Jerod Mayo as the Patriots’ head coach with rookie Drake Maye at quarterback facing Justin Herbert and Chargers coach Jim Harbaugh. Kick-off is at 1 p.m. ET on Saturday.

Kickoff for the Patriots game against the Bills will be at 4:25 p.m. (EST) on Sunday, Dec. 22. The Patriots will be playing in Highmark Stadium in Orchard Park, New York. The current forecast calls for very sunny conditions but also the coldest of the winter so far with a high of 18, according to AccuWeather.

The Buffalo Bills (12-3) will meet AFC East rivals, the New York Jets (4-11), on Sunday, December 29, 2024 at Highmark Stadium. The Bills are heavily favored in this contest, with the line sitting

The Buffalo Bills (11-3) are home at Highmark Stadium to take on division rival New England Patriots (3-11) at 4:25 p.m. Follow here for live updates throughout the game.

The New England Patriots (3-11) and the Buffalo Bills (11-3) meet Sunday in a Week 16 game at Highmark Stadium. Kickoff is scheduled for 4:25 p.m. ET (CBS). Let's analyze BetMGM Sportsbook's

The Buffalo Bills (11-3) host a struggling New England Patriots (3-11) team on Sunday, Dec. 22, 2024 at Highmark Stadium. The Patriots have lost four straight games. Date: Dec. 22 Time: 4:25 p.m. ET Over their last five meetings, Buffalo has tallied four wins versus New England.

Looking at Sunday’s New England Patriots at Buffalo Bills Week 16 NFL odds, lines and trends. Here’s what you need to know.

The Buffalo Bills (12-3) will meet AFC East rivals, the New York Jets (4-11), on Sunday, December 29, 2024 at Highmark Stadium. The Jets are notable underdogs in this one, with the spread posted

Chargers quarterback Justin Herbert threw three touchdown passes as Los Angeles routed the New England Patriots 40-7. By improving to 10-6, the Chargers secured a wild-card berth in the AFC playoffs with one game remaining on their regular-season schedule.