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Detecting problems during protein synthesis with a firefly luciferase-based reporterIn eukaryotic cells—found in animals, plants, and fungi—protein synthesis involves more than ... signaling the successful inhibition of the virus. "Given that luciferase-based assays are ...
AZoLifeSciences on MSN3mon
Peptide Inhibitor Could Revolutionize mRNA-Based TherapiesmRNA carries essential cellular instructions—the chemical blueprint for protein synthesis—from the nucleus ... the 3D ...
News Medical on MSN2d
Research sheds light on resistance to novobiocin in Staphylococcus aureusAnnouncing a new article publication for Zoonoses journal. Methicillin resistant Staphylococcus aureus (MRSA) and Vancomycin ...
Interestingly, the protein ... to and inhibition of cyclin–Cdk complexes, its localization and its ubiquitin-mediated proteolysis. In cancers, p27 is inactivated through impaired synthesis ...
The marine natural product girolline is an inhibitor of protein synthesis. Here, the authors show that girolline is a sequence-selective modulator of eIF5A that can cause ribosome stalling and ...
This simplistic division of the roles of COX-1 and COX-2 drove the search for 'selective' COX-2 inhibitors and further ... is a heme-containing bifunctional protein that sequentially catalyzes ...
All NSAIDs variably inhibit COX-1 and COX-2 and the mechanisms of inhibition fall into three ... Recombinant human protein. NSAIDs variably inhibit prostaglandin H synthase (COX).
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