The LNP-mRNA modality is a novel approach that uses lipid nanoparticles to deliver messenger RNA into cells. The mRNA acts as ...

binds and facilitates release of the mRNA from the ribosome and subsequent dissociation of the ribosome. Comparing Eukaryotic and Prokaryotic Translation The translation process is very similar in ...

In eukaryotic cells like human cells, transcription occurs in the nucleus, and the resulting mRNA is then transported to the cytoplasm for translation. Additionally, eukaryotic mRNA often ...

Table 1: Differences between prokaryotes and eukaryotes. In prokaryotic cells, transcription and translation are coupled, meaning translation begins during mRNA synthesis. 6 In eukaryotic cells, ...

In eukaryotic cells, mRNA decay is catalyzed by two major pathways, and both can be initiated by deadenylation of the polyadenylated (poly-A) tail. After decapping, 5’ to 3’ RNA degradation is ...

It acts like a skilled architect, carefully laying down the blueprint for the mRNA that mirrors the DNA template. In eukaryotic cells, RNA polymerase II is specifically responsible for synthesizing ...

Trypanosomes are parasites that cause sleeping sickness, Chagas disease, and various animal diseases. Diagnosis and treatment remain complex and no effective vaccine has been developed. A better ...

The Kowalinski group at EMBL Grenoble discovered notable differences between the nuclear cap-binding complex in trypanosomes and humans, a critical component in cellular RNA metabolism. Trypanosomes ...

The Merrick laboratory seeks to identify all of the eukaryotic translation initiation factors and ... Although much of the gross work has been determined using hemoglobin mRNA as a model mRNA, it has ...